Результаты (
английский) 2:
[копия]Скопировано!
MMP-8 (also known as neutrophil collagenase and collagenase 2) contained in the specific
cal granules of polymorphonuclear leukocytes (PMNs) as an inactive proenzyme. PMNs plays
out an important role in phagocytosis and have a high capacity to infiltrate the connective
tissue. Various agents, such as IL-1 and IL-8, TNF-α, and GM-CSF stimulate the release of neutrophil MMP-8 - the key enzyme novice destruction of extracellular matrix, especially in pathological inflammatory conditions, rheumatoid arthritis and osteoarthritis. MMP-8 can cleave proteins such as fibronectin, cartilage aggrecan and serpins, as well as the type of the angiotensin peptides, and substance P.
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