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английский) 2:
[копия]Скопировано!
explore the possibility of modeling physiological health status and condition of heart failure in the stand, simulating the systemic circulation, as well as the stand of the cardiovascular system with an implantable device circulatory support.
With the development of medicine and technology alternative to a heart transplant in the terminal stages of heart failure becomes installation circulatory support devices (AVC), supporting the heart pumping function. In order to develop, improve and conduct AVK tests designed stand of the cardiovascular system, allows you to play a variety of state of the physiological cardiovascular system.
For different types of research it is possible to use the stand in several configurations: stand the systemic circulation, stand the cardiovascular system, stand large circulation connecting auxiliary circulatory system, the stand of the cardiovascular system with a connection system circulatory support.
Given the fact that the problem of heart failure is primarily due to the left ventricle, it was decided to explore the possibility of modeling of physiological parameters in the stand, simulating the systemic circulation . studies were carried out: the principle of proportionality of the change in volume and pressure; Frank-Starling law, depending on the force of contraction of the stretching force of the heart muscle; . Resistance principle of the circulatory system of blood flow
integration studies have been conducted in the stand of the cardiovascular system in: AVK left ventricle; AVK right ventricle; AVK left and right ventricles simultaneously.
The results showed that the stand of the cardiovascular system can simulate the physiological parameters and can be used for preclinical testing of AVC. The findings of the results of work will be the basis for further research in the field of design stands the cardiovascular system and of the AVK tests.
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