Эндопротез тазобедренного сустава в

Эндопротез тазобедренного сустава в зоне его контакта с окружающими тканями при трении может вызывать каскад иммунологических реакций, они приводят к резорбции костной ткани. Не менее иммуногенными свойствами обладает костный цемент, который используется для фиксации конструкции в костном ложе. Целью исследования является сравнительная оценка иммунологических показателей периферической крови при цементном и бесцементном энопротезировании тазобедренного сустава. Проведено изучение иммунологических показателей крови 110 больных при первичном эндопротезировании тазобедренного сустава. На основании данных об отдаленных исходах оперативного лечения в сроки до 5,5 лет все больные были разделены на группы с благоприятным (39%) и неблагоприятным (61%) результатом лечения. Лабораторные исследования выполнены до операции, через 3, 10 суток, 1, 3, 6, 9 месяцев и 1, 1.5, 2, 3, 3.5 года после ее проведения. Изучили основные субпопуляции лимфоцитов, функциональную активность клеток, поглотительную активность микрофагоцитов, уровень сывороточных иммуноглобулинов основных классов. Статистическая обработка данных проведена с использованием программ «Microsoft Office Excel 2007» и «Statistica for Windows v.6.1». Установлено, что имплантация эндопротеза вызывает сложный комплекс иммунологических реакций, обусловленных как «неспецифическим» воздействием операционной травмы, так и «специфическим» влиянием эндопротеза. Информативными показателями в системе иммунологического мониторинга при эндопротезировании тазобедренного сустава являются уровень лимфоцитов и Ig M до операции, повышение количества моноцитов и снижение Ig M на третьи сутки после операции.

Результаты (английский) 1:

Endoprosthesis of the hip joint in the zone of contact with surrounding tissue while rubbing can cause a cascade of immune reactions they cause bone resorption. Not less than immunogennymi properties has a bone cement, which is used for bracing design in the bone bed. The aim of the study is a comparative evaluation of peripheral blood immunological parameters in cement and bescementnom hip ènoprotezirovanii. Immunological study of the blood of patients with primary 110 endoprosthetic replacement of the hip joint. Based on data on remote outcomes surgical treatment up to 5.5 years, all the patients were divided into groups with favorable (39%) and adverse (61%) the result of the treatment. Laboratory studies performed prior to surgery, through 3, 10 days, 1, 3, 6, 9 months and 1, 1.5, 2, 3, 3.5 years after its implementation. Examined the main subpopulations of lymphocytes, the functional activity of cells, absorbing mikrofagocitov activity, level of serum immunoglobulins of the major classes. Statistical data processing carried out using Microsoft Office Excel 2007» and «Statistica for Windows v. 6.1. Found that implantation of implant causes complex immunological reactions caused by as "nonspecific" influence operating trauma, and "specific" influence of the Endoprosthesis. Informative indicators of immunological monitoring system during endoprosthetic replacement of the hip joint are the level of lymphocytes and Ig M before the operation, increase the number of monocytes and the lowering of Ig M on the third day after surgery.

Результаты (английский) 2:

hip endoprosthesis in the area of ​​its contact with the surrounding tissues by friction can cause a cascade of immunological reactions, they lead to bone resorption. Not less immunogenic properties has bone cement, which is used for fixing the design in the bone bed. The aim of this study is a comparative assessment of the immunological parameters of peripheral blood at the cement and cementless hip enoprotezirovanii. The study of immunological parameters of blood of 110 patients with primary hip arthroplasty. Based on the data about long-term outcomes of surgical treatment in terms of up to 5.5 years, all the patients were divided into groups with a favorable (39%) and poor (61%) the result of the treatment. Laboratory tests performed prior to operation, after 3, 10 days, 1, 3, 6, 9 months, 1, 1.5, 2, 3, 3.5 years after the conference. Learn the basic subpopulations of lymphocytes, functional activity of cells, an absorption microbivores activity, the level of serum immunoglobulins of the main classes. Statistical data processing was carried out using the «Microsoft Office Excel 2007" program and «Statistica for Windows v.6.1». It was found that the implantation of the endoprosthesis is a complex set of immunological reactions caused by a "non-specific" influence of surgical trauma, and "specific" influence of the implant. Informative indicators in immunological monitoring system during hip arthroplasty is the level of lymphocytes and Ig M before the operation, increasing the number of monocytes and reduced Ig M on the third day after surgery.

Результаты (английский) 3:

эндопротез hip replacements in the zone of its contact with the surrounding tissue in friction can cause a cascade of immunological reactions, they lead to intestinal absorption of bone. at least иммуногенными properties of bone cement, which is used for fixing the box structure in bone marrow. the objective of the study was the comparative evaluation of immunological indicators of peripheral blood in cement and бесцементном энопротезировании hip replacements. the study of immunological indicators of blood эндопротезировании 110 patients with primary hip replacements. on the basis of data on the remote outcome of operative treatment in terms of up to 5.5 years. all the patients were divided into the group with good (39%) and negative (61%) as a result of treatment. laboratory studies performed before operation in 3, 10 days, 1, 3, 6, 9 months and 1, 1.5, 2, 3, 3.5 years after its implementation. have studied the basic субпопуляции lymphocytes, functional activity of the cells поглотительную activity микрофагоцитов, сывороточных main classes of immunoglobulins. statistical analysis of data was carried out with the use of the microsoft office excel 2007 for windows and the following v.6.1». found that implant implantation is a complex immunological reactions caused by "неспецифическим» effects or injury, and the специфическим» influence implant. informative indicators system of immunological monitoring in эндопротезировании hip replacements were lymphocyte and ig m before the operation, increasing the number of моноцитов and reducing ig m on the third day after the operation.