Препараты инсулина короткого действ

Препараты инсулина короткого действия вводят подкожно, но в случае необходимости - внутримышечно или внутривенно. Время начала и пика действия растворимого инсулина короткого действия зависит от пути его введения. Так, пик действия инсулина при внутривенном введении наступает через минуту, интраперитонеальном -через 15 минут, внутримышечном - через 60 минут, подкожном - через 90 минут, а при интраназальном - через 10 минут. При подкожном применении инсулина индивидуальный коэффициент вариации начала и максимального действия состаапяет от 25 до 35 %. Это различие связано со скоростью абсорбции инсулина из места инъекции, зависящей от многочисленных факторов (времени суток и состояния микроциркуляции, введенной дозы, количества подкожно-жировой клетчатки и т.д.).

Результаты (английский) 1:

Short-acting insulin preparations is injected subcutaneously, but if necessary, intramuscularly or intravenously. The start time and maximum short-acting soluble insulin action depends on the way of its introduction. So, the peak of intravenous insulin occurs in minute, intraperitoneal′nom-15 minutes, through no-through 60 minutes, 90 minutes after subcutaneous injection, and in intra-after 10 minutes. When a skin application of insulin individual start and the maximum coefficient of variation of sostaapâet from 25 to 35%. This difference is due to the speed of absorption of insulin injection site that depends on many factors (time of day, and the status of Microcirculation, imposed dose, the amount of subcutaneous fat, etc.).

Результаты (английский) 2:

Short-acting insulin preparations are administered subcutaneously, in case of necessity - intramuscularly or intravenously. Start time and peak action of soluble short-acting insulin is dependent on its route of administration. Thus, peak action of insulin during intravenous administration occurs a minute -through intraperitoneally 15 minutes, intramuscularly - 60 minutes, subcutaneous - 90 minutes, and intranasal - 10 minutes. With subcutaneous administration of insulin individual coefficient of variation of the beginning and the maximum effect sostaapyaet from 25 to 35%. This difference is related to the rate of insulin absorption from the injection site, depending on many factors (the time of day and the state of the microcirculation of the administered dose, the amount of subcutaneous fat, etc.).

Результаты (английский) 3:

Drugs insulin short actions impose a subcutaneous, but if necessary, intramuscular injection or intravenous drug users. The time of the beginning and peak of soluble insulin short action depends on the way its imposition.For example, the peak of insulin intravenous occurs after one minute, интраперитонеальном -after 15 minutes, - - 60 minutes later, modern purified insulin preparations relatively rare cause - 90 minutes, as well as administered - 10 minutes.Modern purified insulin preparations relatively rare cause of insulin individual coefficient of variation start and maximum action состаапяет 25 to 35 %. This difference is associated with speed removals from the insulin injection,Dependent on many factors (time of day, and the anti-inflammatory action, imposed by dose rate, and the amount of subcutaneous fat, etc. ) .