Ключевую роль в борьбе с такими раз

Ключевую роль в борьбе с такими разрывами играет особый фермент АТМ, механизмы включения которого и роль оставались неясными до исследования авторов статьи. Хороненкова и Дьянов попытались выяснить, как работает этот фермент и почему нарушения в его работе вызывают гибель клетки.

Для этого ученые вырастили культуру клеток кожи и проследили за тем, как они реагировали на повреждение ДНК молекулами агрессивного окислителя. Это помогло им выяснить, что ATM реагирует на относительно безобидные единичные, а не на опасные двойные разрывы нитей ДНК, как считалось ранее.

Результаты (английский) 1:

A key role in combating such breaks plays a special enzyme ATM, whose inclusion mechanisms and role remained unclear to the study authors. Horonenkova and D′ânov tried to figure out how it works and why this enzyme abnormality in his work to cause the death of cells.To do this, scientists have cultivated a culture of the skin cells and made sure, as they respond to DNA damage molecules aggressive oxidant. That helped them figure out that ATM responds to relatively harmless individual, rather than the dangerous double breaks DNA strands, as previously thought.

Результаты (английский) 2:

A key role in dealing with such a special enzyme breaks plays ATM switching mechanisms and the role of which remained unclear to the study authors. Khoronenkova Diagne and tried to figure out how this enzyme works and why violations in the work cause the death of cells. To do this, scientists have grown a culture of skin cells and ensure that they respond to DNA damage molecules aggressive oxidizer. This helped them to find out what ATM responds to a relatively innocuous individual, rather than the risk of double-strand breaks in DNA, as previously thought.

Результаты (английский) 3:

a key role in the fight against such therapy plays a special enzyme mechanisms include atm, whose role was unclear to the authors of the study. хороненкова and дьянов tried to figure outhow does this enzyme and why violations in his work is the death cells.

to the scientists bred a culture of skin cells and ensurehow they respond to damage to the dna molecules of aggressive окислителя. it helped them to find out what atm responds to relatively harmless one and not dangerous double perturbation of dnaas previously thought.