Чума - особо опасное инфекционное з

Чума - особо опасное инфекционное заболевание, вызываемое бактериями Yersinia pestis. Проникнув в организм человека или животного Y. pestis способны ингибировать формирование иммунного ответа. В обзоре рассмотрены механизмы ингибирования бактериями Y. pestis формирования неспецифических и специфических иммунных реакций. Рассмотрены факторы патогенности, способствующие формированию устойчивости Y.pestis к фагоцитозу, нарушению полноценной презентации антигена, ингибированию синтеза провоспалительных цитокинов и функциональной активности Т и В-лимфоцитов. Охарактеризована роль гуморальных и клеточных реакций для формирования протективного противочумного иммунитета.

Результаты (английский) 1:

Plague-particularly dangerous infectious disease caused by the bacterium Yersinia pestis. Infiltrating into the human body or animal Y. pestis are able to inhibit the formation of immune response. In a review of the mechanisms of inhibition of bacteria by Y. pestis formation unspecific and specific immune responses. Considered factors of pathogenicity, promoting sustainability, y. pestis to phagocytosis, full-fledged antigen presentation, inhibition of the synthesis of proinflammatory cytokines and the functional activity of t and b-lymphocytes. Described the role of humoral and cellular responses to form proteguogo protivočumnogo immunity.

Результаты (английский) 2:

Plague - especially dangerous infectious disease caused by the bacteria Yersinia pestis. Penetrating into the human or animal Y. pestis capable of inhibiting the immune response. The review deals with the mechanisms of inhibition of bacteria Y. pestis formation of non-specific and specific immune responses. The factors of pathogenicity, foster sustainable Y.pestis to phagocytosis, a full violation of antigen presentation, inhibiting the synthesis of pro-inflammatory cytokines and functional activity of T and B lymphocytes. It described the role of humoral and cellular responses to generate a protective immune antiplague.

Результаты (английский) 3:

Plague is a particularly dangerous infectious disease caused by bacteria is bubo. Infiltrating the human organism or animal Y. pestis can ингибировать formation immune response.The review considered mechanisms for corrosion inhibition Y. pestis bacteria formation of signatures and the specific immune response. Considered pathogenic factors, contributed to sustainability Y.The bubo фагоцитозу, violate a full presentation antigen, rust inhibitors synthesis провоспалительных medical microbiology and functional activity, etc. and in the esr.Last became normal already after described the role and cell reactions for the formation of протективного (photo: Kathryn Utan) immunity.