1 год - работы будут проводиться на

1 год - работы будут проводиться на имеющемся в наличии оборудовании МНИИ "Биоинженерия" (пептидный синтезатор FOCUS-XC, ротационный испаритель RV 10 control V-C, спектрофлюориметр СМ-2203, низкотемпературный термостат для определения вязкости LT-912, лиофильная сушка FreeZone Triad, криотермостат FT-316-40, весы аналитические PA214С и прецизионные Sartorius CPA26P, магнитные мешалки C-MAG HS 7, шкафы сушильные, термостаты суховоздушные, весы лабораторные, термостаты простые и с прозрачной ванной).
В этот период необходима закупка жидкостного хроматографа "LC-20 Prominence" Shimadzu c возможностью очистки до грамма по целевому продукту и дополнительной опцией сбора побочных фракций, первоначально в базовой комплектации, подкрепленным программным обеспечением, и двух специализированных рабочих станций Quantum TXR434-0064R на базе мощных ПК с графическими ускорителями, сертифицированных для расчетов методом молекулярной динамики (МД) (Amber sertified MD system) с библиотеками и базами данных, необходимыми для работ 1 этапа. Наработка опыта эксплуатации приобретенного оборудования, оценка необходимости дополнительных приборных опций.
2 год - для проведения расчетов 2 этапа: специализированная рабочая станция Quantum TXR434-0064R на базе мощных ПК с графическими ускорителями , сертифицированная для расчетов методом молекулярной динамики (МД) (Amber sertified MD system), с расширенным перечнем библиотек и баз данных, закупка комплектующих и расходных материалов для подготовки и проведения пептидного синтеза, специальных систем для хранения образцов, оценка необходимости дополнительных приборных опций, в частности, дополнительного модуля хромато-масс-спектрометрии в составе ВЭХЖ.
3 год - определение перечня необходимых комплектующих, библиотек, баз данных; модернизация собранных лабораторных комплексов с учетом результатов работ и опыта эксплуатации оборудования.

Результаты (английский) 1:

1 year-work will be carried out on the existing available equipment INCLUDE "Bioengineering" (peptide synthesizer FOCUS-XC, Rotary evaporator RV 10 control V-C, it SEE-2203, Circulator for determining viscosity LT-912, liofil′naâ drying FreeZone Triad, kriotermostat FT-316-40, analytical balance PA214S and Sartorius precision CPA26P, magnetic stirrers C-MAG HS 7, drying cabinets, dry-air thermostats, laboratory balance, simple and thermostats with transparent bathtub). During this period requires purchase of liquid chromatograph "LC-20 Prominence" Shimadzu c cleaning capability to gram trust product and the additional option of gathering adverse factions, initially in the basic version, supported software, and two specialized workstations Quantum TXR434-0064R powerful PC-based graphics accelerators certified for calculations of molecular dynamics (MD) (Amber certified MD system) to libraries and databases necessary for phase 1. Hours of operating experience acquired equipment, to assess the need for additional instrumentation options.2 year-for the calculation phase 2: specialized workstation Quantum TXR434-0064R powerful PC-based graphics accelerators certified for calculations of molecular dynamics (MD) (Amber certified MD system), with an extended list of libraries and databases, purchase of spare parts and consumables for preparation and conduct of peptide synthesis, sui generis systems for the storage of samples, to assess the need for additional instrumentation options, inter alia, the additional module chromato-mass spectrometry in the composition VÈHŽ.3 year-definition of a list of required components, libraries, databases; modernization of laboratory complexes collected, taking into account the results and experience of the operation of the equipment.

Результаты (английский) 2:

1 year - work will be carried out on the equipment available MRI "Bioengineering" (peptide synthesizer FOCUS-XC, rotary evaporator RV 10 control VC, spectrofluorimeter CM-2203 low-temperature thermostat for determining the viscosity of LT-912, freeze drying FreeZone Triad, cryothermostats FT -316-40, analytical and precision balances PA214S Sartorius CPA26P, magnetic stirrers C-MAG HS 7, ovens, Dry-air thermostat, laboratory scales, thermostats are simple and transparent bath).
during this period requires purchase of liquid chromatograph "LC-20 Prominence "Shimadzu c possibility of cleaning up program to the desired product and the additional option of collecting adverse factions, initially in the base set, backed up by the software, and two specialized workstations Quantum TXR434-0064R based on powerful PC graphics accelerators are certified for the calculation method of molecular dynamics ( MD) (Amber sertified MD system) with libraries and databases necessary for the work of phase 1. Hours of operation experience acquired equipment, assessment of the need for additional instrumentation options.
2 Year - to settle two stages: a specialized workstation Quantum TXR434-0064R based on powerful PC graphics accelerators certified for payment by molecular dynamics (MD) (Amber sertified MD system ), with an extended list of libraries and databases, purchase of spare parts and consumables for the preparation and conduct of peptide synthesis, special systems for storage of samples, evaluation of the need for additional instrumentation options, in particular, the additional module chromatography-mass spectrometry as part VEHZH.
3 year - determination of the list of required components, libraries, databases; upgrading laboratory facilities gathered in the light of the work and experience of operating equipment.

Результаты (английский) 3:

1 year work will be available in the equipment мнии bioengineering (пептидный synthesizer focus - xc, ротационный evaporator rv 10 control v - c, спектрофлюориметр see - 2203, low thermostat to determine viscosity lt - 912, лиофильная drying FreeZone Triad, криотермостат ft - 316 - 40, the scales of analysis PA214с and precision at CPA26P the magnetic agitator, c - mag hs 7, heating drying, thermostats суховоздушные scales lab ораторные, applications simple and transparent bathroom).in this period, the purchase of liquid is needed хроматографа "lc - 20 Prominence" shimadzu c opportunity of treatment to target the product and an additional option of the side groups, initially in the basic model supported by the software, and two specialized workstations, quantum TXR434 - 0064R based on powerful pc with graphic accelerators, certified for the calculation method of молекуля рной dynamics (md) (amber sertified md system) to libraries and databases necessary for the work 1 phase. accumulation of experience exploitation of equipment, instrument to assess the need for additional options.two year for the calculation of two phase: the specialized workstation quantum TXR434 - 0064R based on powerful pc with graphic accelerators, certified for the calculation method of molecular dynamics (md) (amber sertified md system), with an expanded list of libraries and databases, procurement of components and raw materials for the preparation of пептидного synthesis, special systems for storage samples, evaluation the need for additional instrument options, in particular, an additional module хромато - mass spectrometry of вэхж.3 - the list of necessary components, libraries, and databases; modernization of laboratory systems taking into account the results of the work and experience of operation of the equipment.