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In experiments on 10 cats 3 mass miorelaxanthami immobilized-4 kg using microelectrode techniques and mikroionoforeza method of physiologically active substances influence nootroponah semaxa, and HWS-mexidola 111 on impulse activity of individual neurons in different zones of the cortex. Found that most cortical neurons to čuvctvitel′ny neuroprotective agents. Discovered that the devastating effect mexidol on neurons in over half the cases completely prevents or significantly diminished GABA-negative substances, bikukullinom and pikrotoksinom. Experiments conducted on 10 cats-ligating miorelaxanthami immobilized weight 3-4 kg under the conditions of artificial lung ventilation. For mikroionoforeza used freshly solutions (the solvent served 0, 03 m NaCl) semaxa, mexidole (0.5 m).
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