Теперь мы хотим понять, как данный

Теперь мы хотим понять, как данный фермент включается в ответ на разрывы в одной из двух спиралей ДНК. Это поможет нам разработать новые подходы лечения и способы облегчения судьбы людей, которые страдают от синдрома Луи-Бар и других похожих на него болезней", — заявила Светлана Хороненкова с Химического факультета МГУ, одна из авторов статьи.

Как объясняют Хороненкова и ее коллега Григорий Дьянов, каждый день в каждой клетке нашего организма происходит по 10-20 тысяч мелких поломок в ДНК, которые приводят к разрыву ее спиралей. На эти поломки реагирует целый комплекс белков и сигнальных молекул, которые распознают их, оценивают возможность починки, соединяют разорванные нити или подают сигнал на самоликвидацию клетки.

Результаты (английский) 1:

Now we want to understand how the enzyme is activated in response to gaps in one of the two DNA helices. This will help us to develop new approaches to treatment and ways to alleviate the plight of people who suffer from the syndrome of Louis-Bar and other similar diseases ' on it, "said Svetlana Horonenkova from the Faculty of chemistry, MSU, one of the authors of the article.How to explain the Horonenkova and her colleague Grigory D′ânov, every day in every cell of our body is at 10-20 thousand small breakdowns in the DNA that lead to rupture its spirals. These breakdowns responds a whole complex of proteins and signaling molecules that recognize them, evaluate the possibility of repair, combine broken threads or signal to the self-destruction of a cell.

Результаты (английский) 2:

Now we want to understand how the enzyme is activated in response to a break in one of the two DNA strands. This will help us to develop new treatment approaches and ways to alleviate the plight of people who suffer from the syndrome Louis Bar and others like him disease, "- said Svetlana Khoronenkova with the Chemistry Department of Moscow State University, one of the authors of the article. As explained Khoronenkova and her colleague Gregory Diagne every day in every cell of the body is 10-20 thousand small breakages in the DNA, which lead to rupture of its spiral. In these failure reacts a complex of proteins and signaling molecules that recognize them, assessing the possibility fix, connects broken filament or fed a signal to the cells self-destruct.

Результаты (английский) 3:

now we want to understand how this enzyme is activated in response to a perturbation in one of two spirals of dna. this will help us to develop new approaches to treatment and ways to facilitate the people's lives.suffering from the syndrome of louis bar and other similar diseases, "he said хороненкова with svetlana chemical faculty of moscow university, one of the authors of the article.

how to explain the хороненкова and her colleague gregory дьянов,every day, in every cell of our body is 10 to 20 thousand small breakage in dna that lead to disruption of the spirals. the failure is a complex of proteins and signal moleculeswho know them, assess the possibility of repair of damaged threads, join or gave a signal to shut down the cells.