Через 15 дней после отмены препарат

Через 15 дней после отмены препарата у самцов наблюдалось восстановление этих показателей, а у самок, получавших Мексидол® в дозе 400 мг/кг, увеличивается синтез белка в печени и относительная масса сердца и почек. Тем не менее, макро- и микроскопическое изучение внутренних органов не выявило патологических изменений по сравнению с параметрами контрольных животных через 30 дней введения Мексидола во всех изученных дозах.
Внутрижелудочное введение препарата Мексидол® таблетки, покрытые оболочкой, в течение 25-ти дней неполовозрелым крысам и в течение 30-ти дней неполовозрелым кроликам во всех исследуемых дозах не вызывало место-раздражающего действия.

Результаты (английский) 1:

Through 15 days after the drug was observed in males of these indicators, and females receiving mexidol ® at a dose of 400 mg/kg and increases protein synthesis in the liver and the relative weight of the heart and kidneys. However, macro-and microscopic examination of internal organs have found pathological changes in comparison with parameters of control animals through 30 days of Mexidol all doses. Severe intraventricular infusion mexidol ® tablets, coated liner for 25 days of immature rats and within 30 days of immature rabbits in all doses do not cause the place is irritating.

Результаты (английский) 2:

15 days after discontinuation of the drug males observed recovery of these indicators, and in females receiving MEXIDOL® 400 mg / kg, increased protein synthesis in the liver and the relative weight of the heart and kidneys. Nevertheless, macro- and microscopic examination of internal organs revealed no pathological changes compared with the parameters of the control animals after 30 days of administration Mexidol in all studied doses.
Intragastric administration of the drug MEXIDOL® coated tablets within 25 days immature rats and within 30 days immature rabbits at all doses studied did not cause space-irritant.

Результаты (английский) 3:

15 days after the drug in males there was the restoration of these indicators, and the evolutionary process, receiving Мексидол® in the dose 400 mg/kg, increased protein synthesis in the liver and the relative weight heart and kidney disease.However, macro- and microscopic examination internal organs not revealed pathological changes compared with the parameters control animals 30 days introduction Мексидола in all studied doses.
Внутрижелудочное introduction drug Мексидол® tablets, coated shell,During the 25-days неполовозрелым rats and 30-days неполовозрелым now was comes to exotic animals in all researched doses did not cause the place-irritant.