В) Реакция гиперчувствительности за

В) Реакция гиперчувствительности замедленного типа. В опытах участвовали 18 морских свинок альбиносов. Мексидол вводили однократно в подушечки четырех лапок в дозе 25мг/кг и 250мг/кг (активного вещества). На 21 день опыта на выстриженных участках спины животных вводили внутрикожно разрешающую дозу субстанции препарата 0,05 мл мексидола в концентрации 1мг/мл. контролем служил физ.раствор. Аллергических реакций через 30 минут, 1 час, 24 и 48 часов обнаружено не было.

Результаты (английский) 1:

In delayed-type hypersensitivity reaction). In the experiments involved 18 albino guinea pigs. Mexidol injected once in pads four feet at a dose of 25 mg/kg and 250 mg/kg (active substance). The 21 day experience at vystrižennyh stations back animals injected intracutaneously allowing dose drug substances 0.05 ml mexidola in concentration 1 mg/ml. control served as a physical solution. Allergic reactions through 30 minutes, 1:00, 24 and 48 hours.

Результаты (английский) 2:

C) Delayed-type hypersensitivity reaction. The experiments involved 18 albino guinea pigs. Meksidol administered once to four feet pads dose 25mg / kg and 250mg / kg (active). On day 21 of experience, shorn of the back of animals were injected intradermally resolving dose of 0.05 ml of the drug substance in a concentration mexidol 1mg / ml. He served with saline control. Allergic reactions after 30 minutes, 1 hour, 24 hours and 48 hours was found.

Результаты (английский) 3:

A) The response fact sheet describes what slow-motion type. The prophecy was attended by 18 marine альбиносов sows. Мексидол imposed once the cushions four tabs in the dose 25mg/kg and 250mg/kg (active substances).21 Day experience at the comely: stations spins animals imposed внутрикожно allowing a dose drug substances 0.05 ml мексидола in the concentration of 1mg/ml. control served as phy.solution.Allergic reactions 30 minutes, 1 hour, 24, and 48 hours was found.